Compounded Atropine
Custom Formulation

Compounded Atropine

A custom-prepared low-dose atropine drop, made to the exact concentration your child needs, giving our optometrist precise control when a fixed-strength product isn't the right fit.

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Precise Dosing, Prepared Specifically For Your Child

While Eikance offers a fixed, commercially manufactured 0.01% atropine concentration, some children need a different dose, higher, if 0.01% isn't slowing progression enough, or a different intermediate strength based on their individual response. That's where compounded atropine comes in.

Compounding pharmacies prepare medications to an individual prescription rather than a single fixed formula, allowing our optometrist to specify the exact concentration, commonly between 0.01% and 0.05%, that best suits your child's progression and tolerance. See our Atropine Eye Drops page for how low-dose atropine works more broadly.

compounded-atropine-02.jpg — Compounding Pharmacy Preparation Process
compounded-atropine-03.jpg — Sterile Ophthalmic Compounding Concept

A Well-Established, Regulated Practice

Compounding is a long-standing, regulated part of Australian pharmacy practice, used across many areas of medicine wherever a commercial product doesn't exist at the required strength or formulation. For myopia control, it fills a genuine gap, giving prescribers access to the full range of concentrations studied in major trials, not just the single strength currently available commercially.

We work with compounding pharmacies experienced specifically in ophthalmic preparations, an important detail, since sterile, eye-safe compounding requires particular expertise and quality controls beyond general compounding.

Dose Is Always Individualised

Whether we start a child on Eikance or go straight to a compounded concentration depends entirely on their individual assessment. Our optometrist reviews progression rate, family history and any other relevant factors before recommending a starting dose, and adjusts it over time based on response.

compounded-atropine-04.jpg — Optometrist Reviewing Prescription With Family

Who Compounded Atropine Suits

Compounded atropine suits children who need a concentration other than 0.01%, whether stepping up from an initial dose that wasn't slowing progression enough, or starting at a different strength based on our optometrist's individual assessment.

It's one option within our broader atropine treatment category, itself one of our five treatment options. Our Eikance page explains the fixed-dose alternative.

compounded-atropine-eye-drops-02.jpg — Compounded Atropine Consultation Photo
Common Questions

Compounded Atropine: FAQs

What is compounded atropine?
Compounded atropine is a low-dose eye drop custom-prepared by a specialist compounding pharmacy, made to a specific concentration prescribed by our optometrist for your child individually, rather than a fixed, commercially manufactured strength.
Why would my child need compounded atropine instead of Eikance?
Eikance is available at a single fixed concentration, 0.01%. If your child needs a different concentration, for example a higher dose because 0.01% isn't slowing progression enough, or a lower or intermediate dose for a different reason, compounding allows that flexibility, prepared specifically to our optometrist's prescription.
What concentrations of compounded atropine are used?
Compounded atropine for myopia control is typically prepared in the low-dose range, commonly between 0.01% and 0.05%, reflecting the concentrations studied in major trials such as ATOM2 and LAMP. Our optometrist selects the specific concentration based on your child's progression rate and response.
Is compounded atropine safe?
Yes, when prepared by a reputable, appropriately licensed compounding pharmacy following proper sterile technique and quality standards. Compounding is a well-established, regulated part of pharmacy practice in Australia, widely used across many areas of medicine, not just myopia control.
Is compounded atropine as effective as Eikance?
Effectiveness depends primarily on the concentration used rather than whether it's compounded or commercially manufactured. A compounded 0.01% drop and Eikance's 0.01% drop are expected to work similarly; compounding's main advantage is being able to prescribe a different concentration when 0.01% isn't the right dose for your child.
How do we get compounded atropine?
Our optometrist writes a prescription specifying the exact concentration and quantity needed, which is filled by a compounding pharmacy we work with regularly. We'll guide you through this process, including where to fill it and how often it needs reordering.
How is compounded atropine stored and used?
It's used the same way as any low-dose atropine drop, a single drop each night before bed, and typically needs to be stored as directed by the compounding pharmacy, often refrigerated, since compounded preparations can have different stability profiles to commercial products.
What are the side effects of compounded atropine?
Side effects follow the same dose-dependent pattern as any low-dose atropine, mild light sensitivity and slightly reduced near-focusing ability at higher concentrations within the low-dose range. We monitor every child regularly and adjust the dose if needed.
Can we switch between compounded atropine and Eikance?
Yes, switching is straightforward when clinically appropriate, our optometrist manages the transition and adjusts the prescription as needed based on how your child is progressing and responding.
How does compounded atropine fit into your five treatment options?
It's one form of atropine within our overall atropine treatment category, itself one of our five treatment options alongside OrthoK, contact lenses, myopia control glasses and RLRL. Our Atropine Eye Drops page explains the treatment more broadly.

Find Out If Compounded Atropine Suits Your Child

Book a comprehensive myopia assessment and we'll talk through compounded atropine and how it compares with our other treatment options for your child specifically.

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