Low-Dose Atropine Eye Drops
Pharmacological Treatment

Low-Dose Atropine Eye Drops

A simple nightly eye drop, backed by major international trials, that slows myopia progression through a mechanism entirely different to our optical treatments.

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0.01%–0.05%
typical low-dose concentration range used for myopia control
Nightly
single drop before bed, a simple addition to an existing routine
2 Major Trials
ATOM2 and LAMP, among the largest atropine myopia control studies
Dose-Individualised
concentration set by our optometrist for each child
What Is Low-Dose Atropine?

A Different Mechanism, The Same Goal

Atropine has been used in eye care for well over a century, but its role in myopia control is a more recent, and now very well-studied, development. At low doses, typically between 0.01% and 0.05%, a single drop instilled each night appears to influence receptors involved in regulating how the eye grows, slowing the axial elongation behind progressing myopia.

Unlike our optical treatments, atropine involves no lens wear at all, offering families a genuinely different pathway to the same goal.

Low-Dose Atropine Eye Drop Bottle
How Dosing Works

Individualised, Evidence-Guided Dosing

The right atropine concentration balances effectiveness against side effects, and we set it individually for every child.

A Range Of Concentrations

From 0.01% up to 0.05%, spanning the doses studied in major international trials.

A Clear Dose-Response Relationship

Higher low-dose concentrations generally slow progression more, with a corresponding rise in side effects.

Individualised By Our Optometrist

Starting dose and any adjustment over time are based on your child's progression, response and tolerance.

One Drop, Once A Night

A simple bedtime routine addition, no daytime dosing or lens handling required.

Backed By Major Trials

ATOM2 and LAMP are among the largest, longest-running randomised trials in myopia control.

How It Works

Backed By Major International Trials

Low-dose atropine's evidence base includes some of the largest, longest-running randomised controlled trials in myopia control.

Clinical Trial Data & Nightly Dosing Routine
1

A nightly drop is instilled before bed

A single drop of low-dose atropine, in the eye or eyes being treated, fits easily into an existing bedtime routine.

2

The medication influences eye growth signalling

At low doses, atropine appears to act on receptors within the eye involved in regulating axial elongation, though the exact mechanism isn't fully understood.

3

Effect is confirmed through trial and clinical data

Major trials including ATOM2 and LAMP confirm meaningfully slowed progression compared with placebo, with a clear dose-response relationship.

In plain terms: dose is everything with atropine. Higher concentrations control myopia more but bring more side effects, which is why we individualise every child's treatment.
Benefits

Why Families Choose Atropine

Backed by major trials

Some of the largest, longest-running randomised trials in myopia control.

Simple nightly routine

A single drop before bed, no lens handling or daily insertion.

Individualised dosing

Concentration is set and adjusted specifically for your child's response.

A different mechanism

Works alongside, or independently of, our optical treatment options.

Long track record

Atropine has been used in eye care for well over a century.

Closely monitored

Regular reviews track response and manage any side effects.

Our Clinic

How Eyecare Concepts Prescribes Atropine

We use low-dose atropine as a first-line or combination treatment, prescribed individually and monitored closely.

Step 1

Comprehensive assessment

We assess progression rate, ocular health and suitability, and establish a baseline axial length measurement.

Step 2

Individualised dose selection

Our optometrist selects a starting concentration based on your child's specific progression and circumstances.

Step 3

Ongoing monitoring

We review regularly, tracking axial length, prescription and side effects, adjusting the dose as needed.

Atropine may be a great fit if your child:

  • Prefers drops over lens wear
  • Isn't suited to contacts or OrthoK
  • Is progressing quickly on another treatment
  • May benefit from a combination approach
atropine-eye-drops-02.jpg — Low-Dose Atropine Consultation Photo
Common Questions

Low-Dose Atropine: FAQs

How do atropine eye drops slow myopia?
Atropine is a medication that's been used in eye care for well over a century, and at low doses appears to work on receptors within the eye involved in regulating its growth. The exact mechanism isn't fully understood, but multiple large randomised trials confirm it reliably slows axial elongation and myopia progression in children.
What dose of atropine do you use for myopia control?
We use low-dose atropine, typically in the range of 0.01% to 0.05%, well below the concentrations historically used for other eye conditions. The exact concentration is determined individually by our optometrist based on your child's progression rate, response, and tolerance, and may be adjusted over time.
How effective is low-dose atropine at slowing myopia?
Major trials, including the landmark ATOM2 and LAMP studies, show low-dose atropine meaningfully slows myopia progression compared with placebo, with effectiveness generally increasing at higher concentrations within the low-dose range, alongside a corresponding increase in side effects to weigh against that benefit.
What are the side effects of low-dose atropine?
The most common effects are mild light sensitivity and slightly reduced near-focusing ability, both dose-dependent and generally minor at low concentrations. Serious side effects are rare at these doses. We monitor every child regularly and adjust the dose if side effects are troublesome.
How is atropine different from Eikance or compounded atropine?
Eikance is a TGA-approved, commercially manufactured 0.01% atropine product, while compounded atropine is custom-prepared by a compounding pharmacy at a specific concentration your optometrist prescribes. Both are low-dose atropine, the choice depends on availability, required concentration, and individual circumstances, which we discuss on our dedicated Eikance and compounded atropine pages.
How often is atropine used?
Low-dose atropine is typically administered as a single drop each night before bed in the eye or eyes being treated, a simple addition to an existing bedtime routine.
Can atropine be combined with other myopia control treatments?
Yes. Atropine's mechanism is different from optical treatments like OrthoK, contact lenses, glasses or RLRL, so it's sometimes used alongside another treatment for children progressing quickly, an approach we discuss individually based on your child's specific progression pattern.
Does myopia progress again after stopping atropine?
Some rebound in progression can occur after stopping, particularly with higher low-dose concentrations, which is why we plan the tapering and timing of stopping treatment carefully rather than stopping abruptly without a plan.
What age is atropine suitable for?
Atropine has been studied and used across a wide paediatric age range. We assess suitability individually, considering progression rate, other treatment options, and any relevant medical history.
How does atropine compare with OrthoK, contact lenses or glasses?
Atropine sits in the same top evidence tier as our optical treatments, with a different mechanism and side effect profile, no lens wear at all, but daily drop instillation and monitoring for light sensitivity. Our Myopia Control Treatments page compares all five of our treatment options in detail.

Find Out If Atropine Suits Your Child

Book a comprehensive myopia assessment and we'll talk through low-dose atropine and how it compares with our other treatment options for your child specifically.

Individual results and appropriate dosing vary by child. This page is general information, not medical advice, please speak with one of our optometrists about whether atropine is suitable for your child.

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